Cure neurodevelopmental genetic disorders, please
نویسندگان
چکیده
منابع مشابه
Cure neurodevelopmental genetic disorders, please.
Dramatic, seemingly exponential advances have brought about much hope towards improving the efficacy of management of patients with conditions long-thought incurable, such as neurogenetic disorders. These advances have been both technological and conceptual. They result from refinements in the understanding of pathophysiology and intensive developments of approaches to compensate or bypass the ...
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Advances in genetic tools and sequencing technology in the past few years have vastly expanded our understanding of the genetics of neurodevelopmental disorders. Recent high-throughput sequencing analyses of structural brain malformations, cognitive and neuropsychiatric disorders, and localized cortical dysplasias have uncovered a diverse genetic landscape beyond classic Mendelian patterns of i...
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The effective identification of neurodevelopmental disorders is essential for early diagnosis and provision of intervention services. For many of these conditions, one of the primary domains of abnormality is language development. This review addresses what is known about the earliest indicators of language impairment across a range of neurodevelopmental disorders; consideration is given to bot...
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Development of the human brain occurs in a number of complex preand postnatal stages which are governed by both genetic and environmental factors. Aberrant brain development due to inherited defects may result in a wide spectrum of neurological disorders which are commonly encountered in the clinical field of paediatric neurology. In the work for this thesis, I have investigated the molecular b...
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Neurodevelopmental disorders, sometimes referred to as disorders of intellectual disability (ID), are a large family of conditions of genetic, acquired, or environmental origin that are characterized by deficiencies in cognitive and behavioral functions. While many of these dis‐ orders share similar behavioral phenotypes, they are often accompanied with other features specific to each disorder....
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ژورنال
عنوان ژورنال: Developmental Medicine & Child Neurology
سال: 2012
ISSN: 0012-1622
DOI: 10.1111/j.1469-8749.2012.04373.x